Arterial Stiffness in the Young: Assessment, Determinants, and Implications

Arterial Stiffness in the Young: Assessment, Determinants, and Implications

Arterial stiffness describes the rigidity of the arterial wall. Its significance owes to its relationship with the pulsatile afterload presented to the left ventricle and its implications on ventricular-arterial coupling. In adults, the contention that arterial stiffness as a marker and risk factor for cardiovascular morbidity and mortality is gaining support. Noninvasive methods have increasin...

Ambulatory arterial stiffness index: determinants and outcome.

OBJECTIVES We hypothesized that one minus the slope of diastolic on systolic blood pressure in individual 24-h ambulatory blood pressure recordings (ambulatory arterial stiffness index) might reflect arterial stiffness and predict cardiovascular mortality. METHODS In volunteers and a population recruited in China, we studied concordance between ambulatory arterial stiffness index and establis...

Determinants of arterial stiffness in COPD

BACKGROUND Cardiovascular morbidity and mortality is high in patients with chronic obstructive pulmonary disease (COPD) and arterial stiffness is a potentially modifiable risk factor with added predictive value beyond that obtained from traditional risk factors. Arterial stiffness has been the target of pharmacologic and exercise interventions in patients with COPD, but the effects appear limit...

Arterial stiffness assessment in patients with phenylketonuria

In patients with phenylketonuria (PKU) compliant to diet greater tendency to overweight and higher inflammatory biomarkers levels than controls were reported. Although this could lead to atherogenesis, the elastic properties of large arteries in PKU patients have never been assessed. The aim of this study was to assess arterial stiffness measured by applanation tonometry in PKU patients compare...

Determinants of the ambulatory arterial stiffness index regression line.